Rui-Ping Xiao Biography

Dr. Rui-Ping Xiao was trained as a physiologist and molecular pharmacologist at Tong-Ji Medical University China and at the University of Maryland where she received her M.D. and Ph.D. respectively. Research Interests: Her main scientific focus has been related to receptor-mediated transmembrane signal transduction in the cardiovascular system. Considerable efforts have been put on cardiac aging and heart failure associated changes in G-protein coupled receptor signaling. The breadth of our work covers four different areas: (1) signal transduction mechanisms which underlie the distinct functional roles of b-adrenergic receptor (AR) subtype stimulation in cardiac myocytes; (2) age-and heart failure-related alterations in cardiac responses to b-AR subtype stimulation; (3) interaction of the b-adrenergic signaling pathway with other cardiac sarcolemmal receptor mediated signaling pathways (e.g. opioid adenosine and acetylcholine receptors); and (4) the role of Ca2+/calmodulin-dependent kinase II (CaMKII) in cardiac functional regulation.

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