Bud Frazier Biography

At the Texas Heart Institute, O.H. Frazier, M.D., is the chairman of cardiopulmonary transplantation, program director and chief of the Center for Cardiac Support, and director of cardiovascular surgery research. He is also the director of St. Luke's Episcopal Hospital's Transplant Service. Dr. Frazier has been a pioneer in the treatment of severe heart failure, as well as in the disciplines of heart transplantation and artificial devices that may either replace or aid the human heart's pumping activity, for more than 30 years. THI has become one of the world's leading transplantation and mechanical circulatory support programs as a consequence of his efforts. More than any other surgeon in the world, Dr. Frazier has done over 1,200 heart transplants and implanted over 900 left ventricular assist devices. Dr. Frazier's interest in mechanical circulatory support began in 1969 when he published a research article about the experimental complete artificial heart, which was initially implanted in 1969 by Dr. Denton Cooley, while a student at Baylor College of Medicine. Dr. Frazier worked on creating an implantable left ventricular assist device (LVAD) to help to fail hearts during the 1970s and 1980s, which he initially implanted in 1986 with the HeartMate I, which has now become the most frequently used implantable LVAD in the world. In 2011, Dr. Frazier performed the first successful continuous-flow complete artificial heart implant, replacing a patient's failing heart with two second-generation HeartMate II LVADs.

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